The PLAB 1 exam is the first step to practising as a doctor in the UK
Our fully up to date and reviewed questions reflect the GMC exam to give you the closest revision experience possible to the PLAB exam.
Choose how you want to revise
Revise with my preferences. Choose your difficulty or recap questions you've found hard.
Test myself against recent exam themes and ones curated by BMJ’s editorial team of doctors.
Play under a username and join friends or others for 10 questions. Move up of the daily leaderboard.
On the go
Download the app for offline access. Make revision easily fit into your schedule.
Select the best subscription for your exam date
Join 200,000+ OnExamination users who have successfully become medical professionals
May 2022 Exam
Revise with quality questions and detailed explanations
A 22-year-old man is diagnosed with acute lymphoblastic leukemia and as a part of his treatment, a testicular radiation therapy is planned. The man is concerned about the effect of this treatment on his future fertility.
Which of the following options is the best course of action in this case?
Changing the treatment regimen
Sperm banking before treatment
Testosterone replacement after treatment
Key Learning Point
Chemo- and radiotherapy are very important causes of future infertility, and this issue should be addressed before starting therapy.
This is one of the most contentious issues in cancer therapy. The topic should be discussed at length with the patient (male or female) before initiation of therapy. Ideally, the discussion should involve oncologists, nurses, psychologists, and other technical personnel as necessary.
In males, sperm cryopreservation is the only fertility preservation method. The sperms should be collected before starting chemo/radio therapy. It should be emphasized that once therapy has started, there is a high risk of genetic mutation and other damage to the sperms, it is therefore imperative that the issue be raised before any therapy is initiated.
Hormone replacement therapy has not been found to be effective as a fertility preservation method. Various studies have shown that concerns about fertility are a very important issue for cancer patients, but in some cases, the issue is not raised in time.
Gives me a question everyday that reminds me to continue studying.
The app itself is good. Nice interface, and good organisation of questions. The most beneficial feature is that you can compare yourself with other test takers.
I completed PLAB using OnExamination as a complementary method to boost my revision, I must agree it proved successful. I would recommend anyone to do OnExamination questions repeatedly and read the explanations. Very effective resource for PLAB