Supporting you to pass your SCE in Acute Medicine

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Our questions are mapped to the Specialty Training Curriculum for Acute Internal Medicine, published by the Joint Royal Colleges of Physicians Training Board.

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Demo Question

 

Which of the following may be responsible for a hypokalaemic hypertension?

 Bartter's syndrome

 Diabetic nephropathy

  Liddle's syndrome

 Non-classical congenital adrenal hyperplasia

 Type IV renal tubular acidosis (RTA)



Key Learning Point

 

Liddle's syndrome is typically associated with hypokalaemic hypertension and low renin and aldosterone concentrations - the so-called pseudo-hyperaldosteronism.



Explanation

 

Liddle's syndrome is typically associated with hypokalaemic hypertension and low renin and aldosterone concentrations - the so-called pseudo-hyperaldosteronism.

Bartter's syndrome is associated with hypokalaemia, though hypertension is not a feature.

In type IV RTA, there is a hyporeninaemic hypoaldosteronism, which may also be produced with diabetic nephropathy, hence hyperkalaemia is more typical.


 

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