A 60-year-old man with Wegener's granulomatosis, previously treated with cyclophosphamide, and pulse methylprednisolone is on cyclosporine (100 mg/day), and on a reducing course of oral prednisolone (15 mg/day to 7.5 mg/day) for the last two months.
His vasculitis is well controlled. He was found to have worsening hypertension, despite starting on amlodipine and doxazosin. Urine dipstick and renal ultrasound are normal. He has normal inflammatory markers and FBC over the last few months.
His blood tests are as follows:
What is the most likely cause for deteriorating renal function?
(Please select 1 option)
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